Commentary: Late venous graft failure: Mystery solved?

Mystery solved

Mutant mice lacking the integrin alpha8 subunit exhibit variable defects in kidney development with most mutants missing both kidneys. Several lines of evidence indicate that the known extracellular matrix ligands for integrin alpha8beta1 are either dispensable for or not involved in alpha8beta1 signaling during kidney development. This suggests the presence of an unknown ligand. A novel alpha8...

Predictive Factors of Late Venous Aortocoronary Graft Failure: Ultrastructural Studies

BACKGROUND Venous aortocoronary graft arterialization may precede a preterm occlusion in some coronary artery bypass grafting (CABG) patients. The aim of the present study was to identify ultrastructural variations in the saphenous vein wall that may have an impact on the development of venous graft disease in CABG patients. METHODS The study involved 365 consecutive patients with a mean age ...

Pain: one mystery solved.

The magic angle: a solved mystery.

We resolve the long-standing mysterious discrepancy between the experimental magic angle in EELS--approximately 2theta(E)--and the quantum mechanical prediction of approximately 4theta(E). A relativistic approach surpassing the usually applied kinematic correction yields a magic angle close to the experimental value. The reason is that the relativistic correction of the inelastic scattering cro...

ACTH action on podocytes: mystery solved?

1 2 3 4 5 6 7 8 Editorial focus: 9 10 ACTH action on podocytes: mystery solved? 11 12 13 Paolo Cravedi and Kirk N Campbell 14 15 Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York, New York 16 17 18 Running title: Melanocortins and podocytes 19 20 21 22 23 24 25 Word count: 947 26 27 28 29 30 31 32 33 34 35 Correspondence to: 36 Kirk N Campbell, MD 37 Division of Nephrolo...